Dr. Sam Gijsen

Machine Learning Researcher
Foundation & Generative Models for Physiological Time Series

Currently a Postdoctoral Researcher at:

I research multimodal representation learning and build both foundation models as well as generative models for neural and physiological time series. Previously, I completed a PhD in Computational Cognitive Neuroscience (Freie Universität Berlin) on probabilistic inference and worked on pharmaco-imaging at King's College London and Maastricht University.

Dr. Sam Gijsen

Recent Work


Flow Matching with In-Context Priors for Out-of-Distribution Brain Dynamics

[ICLR26] Brain-Semantoks: Learning Semantic Tokens of Brain Dynamics with a Self-Distilled Foundation Model Sam Gijsen, Marc-André Schulz, Kerstin Ritter
Brain-Semantoks tokenizer overview

We develop a self-distilled foundation model for brain dynamics that pretrains in 2 hours and eliminates the need for finetuning. We stabilize self-distillation for noisy time series through learned tokenization, and find log-linear scaling laws for pretraining data on cross-dataset downstream tasks.

ICLR PaperCodePretrained Models


[ICML25] EEG-Language Pretraining for Highly Label-Efficient Clinical Phenotyping Sam Gijsen, Kerstin Ritter
EEG-Language model overview

First-of-its-kind EEG-language model for downstream clinical tasks. We show a multiple-instance learning extension of the infoNCE loss enables multimodal models which align physiological time series with natural language, yielding more useful representations.

ICML PaperCodePretrained Models


2025 NeurIPS EEG Competition: 7th / 1,183 teams
EEG competition visual summary

Led a small team that placed highly using a multi-modal fusion architecture designed from scratch, without any pretraining. Code and report to come!

Challenge Link


Some Previous Work


Neural surprise in somatosensory Bayesian learning Sam Gijsen, Miro Grundei, Robert T. Lange, Dirk Ostwald, Felix Blankenburg
Neural surprise analyses

Computational modeling of neural signals using information-theoretic measures shows perceptual learning can be described as a process of probabilistic inference.

PLOS Computational BiologyCode


Active inference and the two-step task Sam Gijsen, Miro Grundei, Felix Blankenburg
Active inference two-step task figure

We develop active inference models using probabilistic surprise minimization and show these to describe human sequential decision-making better compared to reinforcement learning.

Scientific ReportsCode


Latest Blog post

Hillsbrad diffusion animation

Hillsbrad Diffusion: A World Diffusion Model Criminally Undertrained
A qualitative look at a world diffusion model undertrained on two hours of sparse exploration of a large map.

Blog post